Dr. Dušica Simijonović

Scientific title: Senior Research Associate
Education: PhD in Chemistry
Laboratory: Bioorganic and bioinorganic chemistry


  • Address: Institute for Information Technologies Kragujevac, Jovana Cvijića bb, 34000 Kragujevac.
  • E-mail: dusicachem@kg.ac.rs

The main part of the research includes the synthesis of potentially biologically active organic and metal-organic compounds. The synthesized compounds belong to the group of phenolic Schiff and Mannich bases, coumarin derivatives, as well as to the group of nitrogenous heterocyclic molecules that contain a piperidine, pyrazolone, pyrazole or pyrazolo-phthalazine unit in their structure, and often a phenolic part. Syntheses are mainly realized using “tools of green organic synthesis”. The structural characterization of the obtained compounds is performed using various experimental and theoretical techniques. Also, a significant part of the research is determination of the antioxidant and anti-inflammatory activity of the obtained products using various in vitro tests.

  1. Marko R. Antonijević, Dušica M. Simijonović, Edina H. Avdović, Andrija Ćirić, Zorica D. Petrović, Jasmina Dimitrić Marković, Višnja Stepanić, Zoran S. Marković, Green One-Pot Synthesis of Coumarin-Hydroxybenzohydrazide Hybrids and Their Antioxidant Potency, Antioxidants, (2021), vol. 10, str. 1106. DOI: 10.3390/antiox10071106.
  2. Dušica Simijonović, Evangelia-Eirini Vlachou, Zorica D. Petrović, Dimitra J. Hadjipavlou-Litina, Κonstantinos E. Litinas, Nevena Stanković, Nezrina Mihović, Milan P. Mladenović, Dicoumarol derivatives: Green synthesis and molecular modelling studies of their anti-LOX activity, Bioorganic Chemistry, (2018), vol. 80, str. 741-752. DOI: 10.1016/j.bioorg.2018.07.021.
  3. Dušica Simijonović, Evangelia-Eirini Vlachou, Konstantinos E. Litinas, Zorica D. Petrović, Vladimir P. Petrović, Synthesis, structural characterization, and molecular docking study of new phthalhydrazide-coumarin hybrids, Journal of Molecular Structure, (2021), vol. 1226, str. 129366. DOI: 10.1016/j.molstruc.2020.129366.
  4. Vesna M. Milovanović, Zorica D. Petrović, Slađana Novaković, Goran A. Bogdanović, Vladimir P. Petrović, Dušica Simijonović, Green synthesis of benzamide-dioxoisoindoline derivatives and assessment of their radical scavenging activity – Experimental and theoretical approach, Tetrahedron (2020), vol. 76, str. 131456. DOI: 10.1016/j.tet.2020.131456.
  5. Dušica Simijonović, Zorica D. Petrović, Vesna M. Milovanović, Vladimir P. Petrović, Goran A. Bogdanović, A new efficient domino approach for the synthesis of pyrazolyl-phthalazine-diones. Antiradical activity of novel phenolic products, RSC Advances, (2018), vol. 8, str. 16663-16673. DOI: 10.1039/c8ra02702a.